Hybrid SPECT/CT Somatostatin Receptor Imaging of Neuroendocrine Tumours
نویسندگان
چکیده
Cilj: Cilj rada bio je procijeniti doprinos jednofotonske emisijske tomografije / kompjutorizirane somatostatinskih receptora (SR SPECT/CT) s 99mTc-EDDA/HYNIC-Tyr3-oktreotidom (99mTc-Tektrotyd) u dijagnostici i procjeni proširenosti bolesti kod pacijenata oboljelih od neuroendokrinih tumora (NET-ova). Ispitanici metode: Retrospektivno analizirano 120 SR SPECT/CT snimanja patohistološki dokazanim NET-om obzirom na vizualizaciju primarnih lezija metastaza. U 45 učinjena pozitronska emisijska tomografija 18F-fluorodeoksiglukozom (18F-FDG PET/CT) te su nalazi uspoređeni nalazima SPECT/CT-a vrijednostima kromogranina A. Rezultati: Od 47 (39 %) upućeno nakon odstranjenja primarne lezije. preostala 73 pacijenta (61 %), 56 (77 primarni tumor vidljiv SPECT/CT-om, a 9 (12 poznata nije akumulirala radiofarmak. 8 (11 nepoznatog primarnog sijela nalaz negativan. 68 (57 metastazama, njih 57 (84 bile vidljive 11 (16 nisu akumulirale (38 kojima učinjen 18F-FDG PET/CT, 27 (60 detekcija metastaza bila sukladna nalazu SPECT/CT-a. Osjetljivost 77 % za lezije 84 metastaze, PET/CT-a 75 76 metastaze. Vrijednosti A pokazale statistički signifikantnu korelaciju slikovne dijagnostike. Zaključci: ima visoku osjetljivost detekciju NET-ova. Osim toga, potvrđena komplementarnost PET/CT-om negativnim nalazom treba učiniti PET/CT obrnuto.
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ژورنال
عنوان ژورنال: Medicina Fluminensis
سال: 2021
ISSN: ['1847-6864', '1848-820X']
DOI: https://doi.org/10.21860/medflum2021_365323